Download BarCharts QuickStudy Heart by Inc. BarCharts PDF

By Inc. BarCharts

Complete, categorised illustrations of the sections of the guts and their capabilities.

Illustrations via award-winning clinical illustrator Vincent Perez.


Chart comprises certain diagrams of:
· move
· anterior center
· posterior center
· inside middle
· nerves & arteries
· starting of diastole
· finish of diastole
· systole
· finish of systole
· middle in diastole
· middle in systole

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Extra info for BarCharts QuickStudy Heart

Example text

Opie, MD, DPhil INTRODUCTION Ventricular Contraction The basic cardiac events of Wiggers’ cycle (Fig. 1) are: (1) left ventricular (LV) contraction, (2) LV relaxation, and (3) LV filling. A natural starting point is with the arrival of calcium ions at the contractile protein that starts actin–myosin interaction and left ventricular contraction. During the initial phase of contraction, the LV pressure builds up until it exceeds that in the left atrium (normally 10 to 15 mmHg), whereupon the mitral valve closes.

Isoform shifts in these proteins play an important role in long-term changes in cardiac function, notably in hypertrophy and heart failure. In the living muscle myosin is aggregated in the thick filaments where the tails are interwoven to form a rigid backbone and the heads project as the cross-bridges (Fig. 4). The cross-bridges in resting muscle are perpendicular to the long axis of the thick filament, whereas in active muscle their position shifts in a manner that allows the cross-bridges to “row” the thin filaments toward the center of the sarcomere (Fig.

Chapter 2 / Molecular and Cellular Basis of Myocardial Contractility 33 Fig. 12. Schematic representation of a calcium release channel (ryanodine receptor or foot protein) in a dyad. (A) View of a dyad in the plane of the bilayer showing the plasma membrane (above) and the subsarcolemmal cisterna (below). The former contains an L-type calcium channel that delivers calcium to a binding site on the sarcoplasmic reticulum calcium release channel. Each of the latter is a tetrameric structure that contains an intramembranous domain (M) and a large foot (F).

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