Download Antioxidants and Cardiovascular Disease by Ulf Landmesser, Helmut Drexler (auth.), Martial G. Bourassa, PDF

By Ulf Landmesser, Helmut Drexler (auth.), Martial G. Bourassa, Jean-Claude Tardif (eds.)

Antioxidants and heart problems, moment version addresses a posh yet very well timed and interesting challenge in cardiovascular medication. it truly is written via famous specialists within the fields of atherosclerosis and antioxidants. it may be of curiosity not just to academicians but additionally to practising physicians. the 1st 5 chapters overview the final recommendations of oxidative tension and their courting to lipid metabolism, endothelial disorder, genetics and transcriptional components. the subsequent seven chapters describe lately outlined markers of oxidative rigidity, pharmacological compounds with antioxidant task, typical antioxidants present in micronutrients and in nutrient-rich diets, and stories the hot proof for his or her efficacy or loss of efficacy in sufferers with heart problems or cardiovascular probability elements. The final seven chapters talk about the aptitude healing advantages of antioxidants in a few cardiovascular stipulations which come with atherosclerosis, restenosis after percutaneous coronary intervention, significant cardiovascular probability elements equivalent to high blood pressure, diabetes mellitus and dyslipidemia, and left ventricular disorder and congestive center failure.

Martial G. Bourassa, M.D. and Jean-Claude Tardif, M.D. are affiliated with the Montreal center Institute, examine middle and division of drugs, school of drugs, collage of Montreal, Montreal, Quebec, Canada.

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Steinbrecher UP, Witztum JL, Parthasarathy S et al. Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism. Arteriosclerosis 1987;7:135-43. Liao F, Andalibi A, Qiao JH et al. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J Clin Invest 1994;94:877-84. Sparrow CP, Parthasarathy S, Steinberg D. Enzymatic modification of low density lipoprotein by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification.

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