Download Advances in Cancer Research, Vol. 3 by Jeese P. Greenstein, Alexander Haddow (Eds.) PDF

By Jeese P. Greenstein, Alexander Haddow (Eds.)

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1948). Bonser (1955) has now suggested that hematite miners should be added t o the list. 9%). The evidence is suggestive, but it is not conclusive, since it is possible that miners with chest symptoms may have been more likely to come to autopsy than men with similar symptoms in nondusty occupations. The extent of the risk has now been defined more closely in the case of asbestos, chromates, and coal gas. S. S. population. They found that, over the period 1940 to 1948, the mortality from lung cancer among white males employed by the plants was 14 times the expected; and among colored males it was 80 times the expected.

Varies Varies 400”-500”C. Suction Combustion Temperature 700°C. 655°C. 470°C. 560°C. Surface Temperature 900°C. 900°C. 700°C. 800°C. + + + + 28 RICHARD DOLL Closely similar temperatures in burning cigarettes have been recorded by Wynder, Graham, and Croninger (1953) and by Hamer (1954), and a similar temperature for combustion in pipes was recorded by Cooper et al. (1932). If Lindsey’s observations on the presence of benzpyrene in the smoke from tobacco burnt in pipes are confirmed, it would seem likely that polycyclic compounds can be formed a t lower temperatures than have, hitherto, been thought to be necessary.

On the other hand, the benzpyrene in cigarette smoke, being dissolved in the form of a fine suspension in a solvent material, may well be more active than the atmospheric benzpyrene, which is largely adsorbed on carbon particles and is, in this state, relatively inactive (Steiner, 1954). Part of the atmospheric benzpyrene is also likely to be filtered off by the nose. Benzpyrene has also been identified in the tar collected from the smoke of “cigarettes” made entirely of paper (Cooper and Lindsey, 1954; Lefemine, 1954).

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